Tests have been developed that detect antigens including the histidine-rich protein II (HRP-II), aldolase, and parasite lactate dehydrogenase (pLDH). Most tests use monoclonal antibodies and detect particular malarial antigens in blood specimens. Rapid diagnostic tests for malaria have been developed that employ immunochromatographic methods based on the detection of malarial antigens present in peripheral blood. Malaria Plasmodium malariae Prevention of re-establishment Rapid diagnostic tests (RDTs).BinaxNOW® Malaria Test, the only available RDT for malaria in the United States. malariae cases are urgently needed for the detection of imported cases in the future. The improved RDTs or nucleic acid tests for P. malariae diagnosis and may threaten the prevention of malaria re-establishment from returned travellers. Both pLDH and aldolase showed relatively conserved and low gene polymorphism rates. All the brands except the worst-performing SD BIOLINE, achieved 75% sensitivity only when the parasite density was higher than 5000 parasites/μL. All tested RDT brands had poor performance in P. The RDTs had a low detection rate (39/69, 56.5%) among P. malariae infection was 3 days, which was longer than that with Plasmodium falciparum (P. The median duration from symptom onset to diagnosis among patients with P.

Furthermore, influential factors were investigated, including parasitaemia load, pLDH concentration and target gene polymorphisms. malariae cases from 2013 to 2020 in Jiangsu Province and evaluated the sensitivity of four parasite enzyme lactate dehydrogenase (pLDH)-targeting RDTs (Wondfo, SD BIONLINE, CareStart and BioPerfectus) and one aldolase-targeting RDT(BinaxNOW) for P.

This study analysed epidemiological features and diagnosis patterns of imported P. malariae) infection diagnosis remains unknown. However, the RDT performance in Plasmodium malariae (P. The accurate and timely diagnosis of malaria is the key in preventing re-establishment, and malaria rapid diagnostic tests (RDTs) are frequently used due to their convenience. For countries that have achieved malaria elimination, the prevention of re-establishment due to infections in returned travellers has become important. 6 Center for Global Health, School of Public Health, Nanjing Medical University, Nanjing, China.

5 National Health Commission Key Laboratory of Parasitic Disease Control and Prevention, Jiangsu Provincial Key Laboratory on Parasite and Vector Control Technology, Jiangsu Institute of Parasitic Diseases, Wuxi, China. 4 Center for Global Health, School of Public Health, Nanjing Medical University, Nanjing, China. 3 National Health Commission Key Laboratory of Parasitic Disease Control and Prevention, Jiangsu Provincial Key Laboratory on Parasite and Vector Control Technology, Jiangsu Institute of Parasitic Diseases, Wuxi, China.1 National Health Commission Key Laboratory of Parasitic Disease Control and Prevention, Jiangsu Provincial Key Laboratory on Parasite and Vector Control Technology, Jiangsu Institute of Parasitic Diseases, Wuxi, China. 2 Center for Global Health, School of Public Health, Nanjing Medical University, Nanjing, China.1 National Health Commission Key Laboratory of Parasitic Disease Control and Prevention, Jiangsu Provincial Key Laboratory on Parasite and Vector Control Technology, Jiangsu Institute of Parasitic Diseases, Wuxi, China.

Rapid diagnostic test for malaria